Effects of ibogaine on acute signs of morphine withdrawal in rats: independence from tremor.
Neuropharmacology May 1, 1992 Stanley D Glick, K Rossman, N C Rao et al. 121 citations
Because of the claim that ibogaine suppresses the symptoms of "narcotic withdrawal" in humans, the effect of ibogaine on naltrexone-precipitated withdrawal signs in morphine-dependent rats was assessed. Morphine was administered subcutaneously through implanted silicone reservoirs for 5 days. Ibogaine (20, 40 or 80 mg/kg, i.p.) or saline was administered 30 min prior to challenge with...