Neurochemical and behavioural interactions between ibogaine and nicotine in the rat.
British Journal of Pharmacology February 1, 1996 M E Benwell, P E Holtom, R J Moran et al. 40 citations
1. In vivo brain microdialysis has been employed to investigate the effects of ibogaine on nicotine-induced changes in dopamine overflow in the nucleus accumbens (NAc) of freely moving rats. The effects of the compound on locomotor responses to nicotine and behaviour in the elevated plus-maze were also examined. 2. No changes were observed in the dopamine overflow or the locomotor activity of...