Y Tang

Ibogaine acts at the nicotinic acetylcholine receptor to inhibit catecholamine release.

Brain Research June 22, 1998 S J Mah, Y Tang, P E Liauw et al. 20 citations

In an effort to determine mechanisms of action of the putative anti-addictive agent ibogaine, we have measured its effects on catecholamine release in a model neuronal system, cultured bovine chromaffin cells. Various modes of stimulating catecholamine release were used including nicotinic ACh receptor activation, membrane depolarization with elevated K+ and Na+ channel activation with...