Differential effects of ibogaine on local cerebral glucose utilization in drug-naive and morphine-dependent rats.
Brain Research April 2, 2004 Beth Levant, Thomas L Pazdernik 17 citations
Ibogaine, a hallucinogenic indole alkaloid, has been proposed as a treatment for addiction to opioids and other drugs of abuse. The mechanism for its putative anti-addictive effects is unknown. In this study, the effects of ibogaine on local cerebral glucose utilization (LCGU) were determined in freely moving, drug-naive, or morphine-dependent adult, male, Sprague-Dawley rats using the...