Ayahoasca: an experimental psychosis that mirrors the transmethylation hypothesis of schizophrenia.
Journal of Ethnopharmacology April 1, 1999 A B Pomilio, A A Vitale, J Ciprian-Ollivier et al. 34 citations
The experimental psychosis observed after drinking Ayahoasca, a South American hallucinogenic beverage from the Amazon Indians, reproduces the pathologic transmethylation theory of schizophrenia. This theory postulates a decrease in the monoamine oxidase (MAO) activity, which results in the accumulation of methylated indolealkylamines, such as bufotenin (5-hydroxy-N,N-dimethyltryptamine),...