Interaction of ibogaine with human alpha3beta4-nicotinic acetylcholine receptors in different conformational states.
The international journal of biochemistry & cell biology September 1, 2010 Hugo R Arias, Avraham Rosenberg, Katarzyna M Targowska-Duda et al. 29 citations
The interaction of ibogaine and phencyclidine (PCP) with human (h) alpha3beta4-nicotinic acetylcholine receptors (AChRs) in different conformational states was determined by functional and structural approaches including, radioligand binding assays, Ca2+ influx detections, and thermodynamic and kinetics measurements. The results established that (a) ibogaine inhibits (+/-)-epibatidine-induced...
DOI: 10.1016/j.biocel.2010.05.011 (opens in new tab)
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Ibogaine: ibogaine
Human brain receptor
Key brain receptors
Receptor's channel
+9