Neuropathic and inflammatory antinociceptive effects and electrocortical changes produced by Salvia divinorum in rats.
Journal of Ethnopharmacology July 12, 2017 Karina Simón-arceo, Ma Eva González-trujano, Ulises Coffeen et al. 26 citations
Salvia divinorum is a medicinal plant traditionally used in hallucinogenic ethnopharmacological practices and for its analgesic and antinflammatory properties. Its active compounds include diterpenes known as salvinorins which act as potent κ opioid receptor agonists. Given its effects in acute animal models of pain, as well as its antinflammatory attributes, we decided to investigate the...