Identification of clerodane diterpene modifying cytochrome P450 (CYP728D26) in Salvia divinorum - en route to psychotropic salvinorin A biosynthesis.
Physiologia plantarum 2024 Iris Ngo, Rahul Kumar, Liang Li et al. 6 citations
Salvia divinorum is a hallucinogenic plant native to the Oaxaca in Mexico. The active ingredient for psychotropic effects in this plant is salvinorin A, a potent and highly selective κ-opioid receptor agonist. Salvinorin A is distinct from other well-known opioids, such as morphine and codeine, in that it is a non-nitrogenous diterpenoid with no affinity for μ-opioid receptor, the prime...
DOI: 10.1111/ppl.14569 (opens in new tab)
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Salvinorin a
Pain management
Non-opioid pain relief
Alternative analgesics
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