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Zachary I Merhavy

2 papers in the library · 1 citation · publishing 2024-2025

Papers

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Exploring the Neuroprotective and Neuropsychiatric Symptom Management Potential of Ketamine in Alzheimer's Disease.

Cureus June 1, 2025 Amy Avakian, Zachary I Merhavy 1 citation

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, synaptic dysfunction, and neuroinflammation. Despite extensive research, current therapeutic options offer limited symptomatic relief without altering disease progression. Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist traditionally used as an anesthetic, has garnered...

Navigating Buprenorphine Therapy: A Closer Look at Microdosing vs. Macrodosing for Pain Management and Opioid Addiction - A Narrative Review.

Addiction & health October 1, 2024 Zachary I Merhavy, Marcos Flores, Eliu Rivera et al.

Buprenorphine therapy has emerged as a primary therapy method for both opioid addiction and chronic pain; however, the «one size fits all» approach to buprenorphine administration is no longer tenable. This review analyzes the pharmacology of both dosing approaches and their clinical outcomes, safety profiles, and societal implications, providing valuable insights for healthcare professionals....