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Nicole Perkins

3 papers in the library · 6 citations · publishing 2022-2025

Papers

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Epigenetic aging and DNA methylation biomarker changes following ketamine treatment in patients with MDD and PTSD: a pilot study.

Translational Psychiatry October 31, 2025 Kristin L Dawson, Athena May Jean M. Carangan, Jessica Klunder et al. 2 citations

Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are debilitating psychiatric conditions associated with poor health outcomes similarly observed in non-pathological aging. Ketamine is a dissociative anesthetic and NMDA receptor antagonist with demonstrated rapid reduction in symptoms associated with Treatment Resistant Depression (TRD) and PTSD. Ketamine's effects on...

Ketamine treatment effects on DNA methylation and Epigenetic Biomarkers of aging

medRxiv Preprint Server September 10, 2024 Kristin L Dawson, Athena May Jean M. Carangan, Jessica Klunder et al. 4 citations preprint

Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are debilitating psychiatric conditions associated with poor health outcomes similarly observed in non-pathological aging. Ketamine is a dissociative anesthetic and NMDA receptor antagonist with demonstrated rapid reduction in symptoms associated with Treatment Resistant Depression (TRD) and PTSD. Ketamine’s effects on...

Effects of Kindness- and Compassion-Based Meditation on Wellbeing, Prosociality, and Cognitive Functioning in Children and Adolescents: a Systematic Review

Mindfulness September 1, 2022 Nicole Perkins, Taranjit Sehmbi, Patrick Smith

AbstractObjectivesInterventions involving kindness- and compassion-based meditation (KCBM) have been shown to have various benefits for adults, and there is growing interest in using KCBMs with children. This systematic review explores the effects of KCBM on wellbeing, prosociality, and cognitive functioning in children and adolescents.MethodsStudies were eligible if they examined interventions...