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Tavis L. Mendez

2 papers in the library · 6 citations · publishing 2024-2025

Papers

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Epigenetic aging and DNA methylation biomarker changes following ketamine treatment in patients with MDD and PTSD: a pilot study.

Translational Psychiatry October 31, 2025 Kristin L Dawson, Athena May Jean M. Carangan, Jessica Klunder et al. 2 citations

Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are debilitating psychiatric conditions associated with poor health outcomes similarly observed in non-pathological aging. Ketamine is a dissociative anesthetic and NMDA receptor antagonist with demonstrated rapid reduction in symptoms associated with Treatment Resistant Depression (TRD) and PTSD. Ketamine's effects on...

DOI: 10.1038/s41398-025-03683-y (opens in new tab) Full text (opens in new tab)

Ketamine treatment effects on DNA methylation and Epigenetic Biomarkers of aging

medRxiv Preprint Server September 10, 2024 Kristin L Dawson, Athena May Jean M. Carangan, Jessica Klunder et al. 4 citations preprint

Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are debilitating psychiatric conditions associated with poor health outcomes similarly observed in non-pathological aging. Ketamine is a dissociative anesthetic and NMDA receptor antagonist with demonstrated rapid reduction in symptoms associated with Treatment Resistant Depression (TRD) and PTSD. Ketamine’s effects on...

DOI: 10.1101/2024.09.10.24313258 (opens in new tab) Full text (opens in new tab) Depression PTSD Ketamine infusions Mental health +7