Philosophy, Psychiatry, & Psychology
October 1, 2025
Lucas F. Borkel, Tobías Fernández-Borkel, Jaime Rojas-Hernández et al.
This paper examines delusions and psychedelic experiences as sources of both epistemic risk and benefit. Although these states are often seen as irrational or pathological, the paper explores their potential epistemic and psychological benefits, such as fostering emotional adaptation and creativity. The paper cautions against interpreting subjective experiences as metaphysical truths, which...
ACS Pharmacology & Translational Science
July 16, 2025
Tobías Fernández-Borkel, Lucas F Borkel, Jaime Rojas-Hernández et al.
3 citations
The therapeutic potential of psychedelic substances, particularly psilocybin, for treatment-resistant depression (TRD) has garnered considerable attention. However, the necessity of subjective psychedelic experiences for therapeutic efficacy remains unclear, creating a critical gap in the field. To determine whether subjective psychedelic experiences induced by psilocybin are required for its...
Veterinary medicine and science
July 1, 2025
Elisa Hernández-Álvarez, Lucas F Borkel, Jaime Rojas-Hernández et al.
3 citations
This pilot study explored the potential of microdosing 1-cyclopropionyl-d-lysergic acid diethylamide (1cp-LSD) to treat canine anxiety. A single-case study was conducted on a 13-year-old female dog with severe separation anxiety, who was treated with 5 µg of 1cp-LSD every 3 days for a month. Anxiety was assessed before, after, and 1 month following treatment using a validated questionnaire. The...
Veterinary research communications
December 1, 2024
Luis Alberto Henríquez-Hernández, Ignacio García-Serrano, Domingo J Quintana-Hernández et al.
4 citations
Anxiety affects 14-20% of dogs. Pharmacological treatments often fail. Psychedelics have shown to be useful for anxiety and depression in humans, but their veterinary use remains unexplored. We aimed to determine the effects of low-dose 1-cyclopropionyl-d-lysergic acid diethylamide (1cp-LSD) administered in a single dose to a dog, to observe the effect and establish the safety of the substance....