Psychedelics
March 7, 2026
Skylar J. Gaughan, Jae Sevelius, Rafael Lancelotta et al.
Psychedelics have long histories of use in Indigenous communities for healing, spiritual, and ceremonial purposes. In contrast, Western psychedelic science has emerged through frameworks shaped by colonization, racism, and medicalization. These systems often marginalize and exclude the very communities most impacted by trauma, including transgender and gender-expansive (TGE) individuals,...
Frontiers in Psychiatry
January 22, 2026
Jae Sevelius, Rachel Lynn Golden, B. Stott et al.
1 citation
Introduction Transgender and gender-expansive people experience high rates of depression, anxiety, and trauma-related distress, yet few evidence-based interventions are tailored to their needs. Kindred is a novel, group-based ketamine-assisted psychotherapy (KAP) program that integrates cognitive processing therapy (CPT) to address identity-based trauma. Methods This mixed-methods pilot study...
Journal of Psychoactive Drugs
June 18, 2025
Rafaelle Lancelotta, Meghan DellaCrosse, Diana Quinn et al.
7 citations
This study investigated subjective psychedelic experiences in the global LGBTQIA+ population. Using validated measures of acute psychedelic effects, psychological flexibility, gender and sexual identity attitudes, adverse experiences, and mental health, we examined self-reported changes in identity and mental health outcomes following psychedelic use. A total of 346 individuals completed the...
International Journal of Transgender Health
March 19, 2025
Skylar J. Gaughan, Angie R. Wootton, Daphne Krantz et al.
6 citations
Background: While psychedelic medicines have increasingly been studied for their utility as an adjunct to psychotherapy, transgender and gender-expansive (TGE) individuals have rarely been the focus of psychedelic research. This study examines TGE people's naturalistic, non-clinical psychedelic experiences to explore how TGE people use psychedelics and how they describe relationships between...
Frontiers in Psychiatry
October 10, 2022
Christopher S. Stauffer, Melanie Brown, Dee Adams et al.
40 citations
Introduction Transgender and gender diverse (TGD) people experience stigma, discrimination, trauma, and post-traumatic stress disorder (PTSD) at higher rates compared to the general population; however, TGD people have been underrepresented in PTSD research. Clinical trials of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy demonstrate promising safety and efficacy for the...
Journal of Evolutionary Psychology
September 21, 2020
Monnica T. Williams, Amy Bartlett, Tim Michaels et al.
7 citations
Abstract Equity and diversity are essential to the development of inclusive psychedelic research. However, oversights and misattributions are common, particularly when it comes to accounts of important psychedelic moments and key figures. Dr. Valentina Pavlovna Wasson is an important early contributor to the growth of Western psychedelic science but remains under-recognized. Psychedelic...
Journal of Psychedelic Studies
July 1, 2019
Jamilah R. George, Timothy I. Michaels, Jae Sevelius et al.
222 citations
In recent years, the study of psychedelic science has resurfaced as scientists and therapists are again exploring its potential to treat an array of psychiatric conditions, such as depression, post-traumatic stress disorder, and addiction. The scientific progress and clinical promise of this movement owes much of its success to the history of indigenous healing practices; yet the work of...