Prefrontal and striatal glutamate plays an important role in modulating striatal dopamine levels and an imbalance in regional glutamate has been identified in several psychiatric conditions. We hypothesized that this imbalance also exists in cannabis use disorder (CUD). We recently quantified the difference in glutamate of dorsal anterior cingulate (dACC) and striatum regions in the...
The default mode network (DMN) is a complex dynamic network that is critical for understanding cognitive function. However, whether dynamic topological reconfiguration of the DMN occurs across different brain states, and whether this potential reorganization is associated with prior learning or experience is unclear. To better understand the temporally changing topology of the DMN, we...