Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain.
Nature Communications March 11, 2024 Andrea I. Luppi, Lynn Uhrig, Jordy Tasserie et al. 43 citations
A central challenge of neuroscience is to elucidate how brain function supports consciousness. Here, we combine the specificity of focal deep brain stimulation with fMRI coverage of the entire cortex, in awake and anaesthetised non-human primates. During propofol, sevoflurane, or ketamine anaesthesia, and subsequent restoration of responsiveness by electrical stimulation of the central...