High-order brain interactions in ketamine during rest and task: A double-blinded cross-over design using portable EEG.
Research Square March 21, 2024 Agustin Ibanez, Rubén Herzog, Florentine Barbey et al. 1 citation
In a double-blinded cross-over design, 30 adults (mean age = 25.57, SD = 3.74; all male) were administered racemic ketamine and compared against saline infusion as a control. Both task-driven (auditory oddball paradigm) and resting-state EEG were recorded. HOI were computed using advanced multivariate information theory tools, allowing us to quantify nonlinear statistical dependencies between...