Richard E Rosch

Selective Prefrontal Disinhibition in a Roving Auditory Oddball Paradigm Under N-Methyl-D-Aspartate Receptor Blockade.

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging February 2019 Richard E Rosch, Ryszard Auksztulewicz, Pui Duen Leung et al.

Disturbances in N-methyl-D-aspartate receptors (NMDARs)-as implicated in patients with schizophrenia-can cause regionally specific electrophysiological effects. Both animal models of NMDAR blockade and clinical studies in patients with schizophrenia have suggested that behavioral phenotypes are associated with reduction in inhibition within the frontal cortex. Here we investigate event-related...