Mansoureh Soleimani

2 papers in the library · publishing 2013-2015

Papers

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Expression of bax and bcl2 Genes in MDMA-induced Hepatotoxicity on Rat Liver Using Quantitative Real-Time PCR Method through Triggering Programmed Cell Death.

Iranian Red Crescent medical journal November 26, 2015 Mitra Behroozaghdam, Mehrdad Hashemi, Gholamreza Javadi et al.

Background: 3-4methylenedioxymethamphetamine (MDMA) is a synthetic and psychoactive drug, which is known popularly as Ecstasy and has toxic effects on human organs. Objectives: Considering the potential toxic interaction, this study was performed to quantify the expression of bax and bcl2 genes in MDMA-induced hepatotoxicity on rat liver. Subsequently, we evaluated pentoxifylline as a possible...

DOI: 10.5812/ircmj.24609 Full text MDMA Anti-apoptotic gene Pentoxifylline Pro-apoptotic gene +1

Protective effects of N-acetylcysteine on 3, 4-methylenedioxymethamphetamine-induced neurotoxicity in male Sprague-Dawley rats.

Metabolic Brain Disease December 2013 Sara Soleimani Asl, Kazem Mousavizadeh, Bagher Pourheydar et al.

Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) leads to spatial memory impairment and hippocampal cell death. In the present study we have examined the protective effects of N-acetyl-L-cysteine (NAC) on MDMA-induced neurotoxicity. A total of 56 male Sprague Dawley rats (200-250 g) received twice daily intraperitoneal (IP) injections of 5, 10 or 20 mg/kg MDMA plus NAC (100 mg/kg). Rectal...

DOI: 10.1007/s11011-013-9423-1 Full text