Expression of bax and bcl2 Genes in MDMA-induced Hepatotoxicity on Rat Liver Using Quantitative Real-Time PCR Method through Triggering Programmed Cell Death.
Iranian Red Crescent medical journal November 26, 2015 Mitra Behroozaghdam, Mehrdad Hashemi, Gholamreza Javadi et al.
Background: 3-4methylenedioxymethamphetamine (MDMA) is a synthetic and psychoactive drug, which is known popularly as Ecstasy and has toxic effects on human organs. Objectives: Considering the potential toxic interaction, this study was performed to quantify the expression of bax and bcl2 genes in MDMA-induced hepatotoxicity on rat liver. Subsequently, we evaluated pentoxifylline as a possible...
DOI: 10.5812/ircmj.24609 (opens in new tab)
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MDMA
Anti-apoptotic gene
Pentoxifylline
Pro-apoptotic gene
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