Treadmill exercise alters ecstasy- induced long- term potentiation disruption in the hippocampus of male rats.
Metabolic Brain Disease October 2017 Azam Sajadi, Iraj Amiri, Alireza Gharebaghi et al.
3, 4-methylenedioxymethamphetamine (MDMA) or ecstasy is a derivative of amphetamine that leads to long term potentiation (LTP) disruption in the hippocampal dentate gyrus (DG). Exercise has been accepted as a treatment for the improvement of neurodegenerative disease. Herein, the effects of exercise on the MDMA- induced neurotoxicity were assessed. Male Wistar rats received intraperitoneal...
DOI: 10.1007/s11011-017-0046-9 (opens in new tab)
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Ecstasy
Bdnf
Ltp
Treadmill exercise