Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications
Scientific Reports April 27, 2017 Isaac Cohen, Tigran Makunts, Rabia Samady Atayee et al. 27 citations
Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of eight million reports from the FDA Adverse Effect Reporting System. The results of the examination of population scale data revealed that patients...