Design, Synthesis and Biological Evaluation of Novel Ketamine Derivatives as NMDAR Antagonists.
Molecules (Basel, Switzerland) May 23, 2024 Shiyun Li, Bin Wen, Wei Zhao et al. 4 citations
Depression is a chronic, severe, and often life-threatening neurological disorder. It not only causes depression in patients and affects daily life but, in severe cases, may lead to suicidal behavior and have adverse effects on families and society. In recent years, it has been found that sub-anesthetic doses of ketamine have a rapid antidepressant effect on patients with treatment-resistant...