Kawthar A. Mohamed

In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa

Scientific Reports November 23, 2020 A. Zagzoog, Kawthar A. Mohamed, H. J. J. Kim et al.

The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of ∆9-tetrahydrocannabinol (∆9-THC) and cannabidiol (CBD), comparatively little is known about the pharmacology of the less-abundant plant-derived (phyto) cannabinoids. The best-studied transducers of cannabinoid-dependent effects are type 1 and type 2 cannabinoid receptors (CB1R, CB2R). Partial agonism of CB1R...