Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are enhanced following cocaine self-administration.
Brain Research May 1, 1995 S R White, G C Harris, K M Imel et al.
Rats were allowed to self-administer cocaine during a 3-h session for 15 days. One to 11 days after the last cocaine exposure, rats were anesthetized with urethane and effects of microiontophoretically-applied dopamine on glutamate-evoked firing of neurons in the nucleus accumbens and in the caudate/putamen were tested. Dopamine produced a dose-dependent inhibition of glutamate-evoked firing in...
DOI: 10.1016/0006-8993(95)00309-e (opens in new tab)
Brain
Caudate nucleus
Putamen
Nucleus accumbens
+11