O D Gulati

Effect of clozapine and molindone on plasma and brain levels of mescaline in mice.

European Journal of Drug Metabolism and Pharmacokinetics October 1, 1984 N S Shah, O D Gulati

Levels of unchanged mescaline were examined in the plasma and brain of albino Swiss-Webster mice pretreated with various doses of either clozapine or molindone. In clozapine treated mice, the mescaline levels were statistically significantly higher at 2 and 3 h with 7.5 and 15.0 mg/kg and at 1, 2 and 3 h with 30 mg/kg. Molindone at 4.0 and 8.0 mg/kg produced no significant effect; at 16.0 and...