A randomised, open-label, pragmatic pilot comparison of oral and intravenous ketamine in treatment-resistant depression.
Asian Journal of Psychiatry September 1, 2024 Pn Suresh Kumar, Vikas Menon, Chittaranjan Andrade 12 citations
For depression, ketamine is more conveniently administered by oral than by intravenous (iv) routes. The relative antidepressant efficacy of oral vs iv ketamine is unknown. To assess the acute efficacy and the persistence of improvement with open-label oral versus iv ketamine in outpatients with treatment-resistant depression (TRD). Adults with TRD were randomized to oral (N=30) or IV (N=31)...