Influence of structural characteristics on the binding of synthetic cannabinoids from the JWH family to the CB1 receptor: A computational study.
Journal of molecular graphics & modelling January 2024 Krishna Chaturvedi, Caroline S Anthony, Pankaj Pandey et al.
Synthetic cannabinoids, including some from the John W. Huffman (JWH) family, emerged on the drug scene around 2004 as "alternative marijuana," despite being considerably more potent than marijuana. Like Δ9-tetrahydrocannabinol (THC), the principal psychoactive ingredient in marijuana, synthetic cannabinoids have also been found to interact with cannabinoid receptors CB1 and CB2, found in the...
DOI: 10.1016/j.jmgm.2023.108620 (opens in new tab)
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Cannabinoid receptor 1
Docking
Jwh-series
Molecular dynamics
+1