Lab-based studies examining the effects of cannabis administration on human behavior compromise ecological validity due to the influence of set and setting. Contextual factors of clinical settings have long been recognized as producing measurable changes in physiology, emotionality, and cognition. Among people who use drugs, these settings may be associated with higher levels of perceived...
Carolyn M. L. Crawford, Zach Walsh, W. Francois Louw et al.
Chronic pain is a prevalent and disabling condition, making access to safe and effective pain treatments a public health priority. Early but encouraging results have emerged from research investigating the therapeutic potential of psilocybin for people living with chronic pain (PLCP). This growing line of work urges an understanding of PLCP’s receptivity to this treatment. Aim. The primary aim...