Metabolic and respiratory alterations following acute exposure to high-THC and high-CBD cannabis smoke in female mice
Journal of Cannabis Research August 26, 2026 Ario Safaeian, Kaylen M. Young, John G. Howland et al.
Abstract Background Cannabis use has increased in recent years due to legalization. Smoking cannabis leads to inhalation of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in addition to other particles and gas in the smoke matrix as a result of combustion. The effect of THC on breathing pattern and metabolism has been characterized, but the influence of CBD and the smoke matrix on...