THE NEURONAL CIRCUITS IMPLICATED IN THE PHENCYCLIDINE-INDUCED BEHAVIORAL IMPAIRMENTS AND THERAPEUTIC AND SIDE EFFECTS OF ARIPIPRAZOLE
International Journal of Neuropsychopharmacology February 1, 2025 *Ami Ono, D. Koan, S. Asano et al.
Abstract Background Schizophrenia is a psychiatric disorder characterized by positive and negative symptoms and cognitive impairments. Second-and third-generation antipsychotics alleviate not only positive symptoms but also negative symptoms and cognitive impairments, with a lower liability for extrapyramidal symptoms (EPS).Accumulating evidences suggest that dopaminergic mesocorticolimbic and...