Abstract Background Schizophrenia is a psychiatric disorder characterized by positive and negative symptoms and cognitive impairments. Second-and third-generation antipsychotics alleviate not only positive symptoms but also negative symptoms and cognitive impairments, with a lower liability for extrapyramidal symptoms (EPS).Accumulating evidences suggest that dopaminergic mesocorticolimbic and...
AbstractTo elucidate the role of the serotonin (5‐HT)2A/2C receptors in 3,4‐methylenedioxymethamphetamine (MDMA)‐induced neurotoxicity, MDMA was administered to rats and the presence of the serotonin transporter (5‐HTT) was assessed at the protein level with immunohistochemistry (IHC), and the RNA level with a Northern blotting technique. d‐lysergic acid diethylamide (LSD) and MDL 11,939 were...