Drugs with glutamate-based mechanisms of action in psychiatry.
Pharmacological Reports December 1, 2024 Adrian Andrzej Chrobak, Marcin Siwek 11 citations
Psychopharmacotherapy of major psychiatric disorders is mostly based on drugs that modulate serotonergic, dopaminergic, or noradrenergic neurotransmission, either by inhibiting their reuptake or by acting as agonists or antagonists on specific monoamine receptors. The effectiveness of this approach is limited by a significant delay in the therapeutic mechanism and self-perpetuating growth of...
DOI: 10.1007/s43440-024-00656-8 (opens in new tab)
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Serotonin
Antidepressant drugs
Antipsychotic drugs
Excitotoxicity
+7