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Kevin Johnston

3 papers in the library · 1 citation · publishing 2021-2024

Papers

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Effects of Ketamine on Frontoparietal Interactions in a Rule-Based Antisaccade Task in Macaque Monkeys.

The Journal of neuroscience : the official journal of the Society for Neuroscience December 11, 2024 Liya Ma, Nupur Katyare, Kevin Johnston et al. 1 citation

Cognitive control is engaged by working memory processes and high-demand situations like antisaccade, where one must suppress a prepotent response. While it is known to be supported by the frontoparietal control network, how intra- and interareal dynamics contribute to cognitive control processes remains unclear. N-Methyl-d-aspartate glutamate receptors (NMDARs) play a key role in prefrontal...

Effects of ketamine on frontoparietal interactions during working memory in macaque monkeys

bioRxiv Preprint Server May 16, 2023 Liya Ma, Nupur Katyare, Kevin Johnston et al. preprint

Schizophrenia is known as a syndrome of dysconnection among brain regions. As a model for this syndrome, low doses of N-methyl-D-aspartate (NMDA) receptor antagonists, such as ketamine, produce schizophrenia-like symptoms and cognitive deficits in healthy humans and animals. One of such deficits is impaired working memory, a process that engages an extended network of both frontal and parietal...

Ketamine disrupts gaze patterns during face viewing in the common marmoset

bioRxiv Preprint Server February 16, 2021 Janahan Selvanayagam, Kevin Johnston, Raymond K. Wong et al. preprint

Faces are stimuli of critical importance for primates. The common marmoset (Callithrix jacchus) is a promising model for investigations of face processing, as this species possesses oculomotor and face processing networks resembling those of macaques and humans. Face processing is often disrupted in neuropsychiatric conditions such as schizophrenia (SZ) and thus it is important to recapitulate...