Alisha N Dua

Structural neural plasticity evoked by rapid-acting antidepressant interventions.

Nature Reviews Neuroscience February 1, 2025 Clara Liao, Alisha N Dua, Cassandra Wojtasiewicz et al. 60 citations

A feature in the pathophysiology of major depressive disorder (MDD), a mood disorder, is the impairment of excitatory synapses in the prefrontal cortex. Intriguingly, different types of treatment with fairly rapid antidepressant effects (within days or a few weeks), such as ketamine, electroconvulsive therapy and non-invasive neurostimulation, seem to converge on enhancement of neural...