Skip to content

Vitalis Briedis

2 papers in the library · 102 citations · publishing 2005-2008

Papers

Sort Most recent Most cited

Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review.

Human & Experimental Toxicology March 1, 2008 R Maciulaitis, Violeta Kontrimaviciūte, Françoise M M Bressolle et al. 102 citations

Ibogaine is an indole alkaloid derived from the bark of the root of the African shrub Tabernanthe iboga. Psychoactive properties of ibogaine have been known for decades. More recently, based on experimental data from animals and anectodal reports in human, it has been found that this drug has anti-addictive effects. Several patents were published between 1969 and 1995. The pharmacology of...

Quantitation of ibogaine and 12-hydroxyibogamine in human plasma by liquid chromatography with fluorimetric detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences August 5, 2005 Violeta Kontrimaviciūte, Michel Larroque, Vitalis Briedis et al.

A high-performance liquid chromatographic (HPLC) method with fluorimetric detection was developed for the simultaneous determination of ibogaine and noribogaine in human plasma using fluorescein as internal standard. This method involved a solid phase extraction of the compounds from plasma using N-vinylpyrrolidone-divinybenzene copolymer cartridges. Separation of the three analytes was...