Vojnosanitetski Pregled
July 2011
Nadica S Marinković, Zivorad Malicevic, Jovan Dimitrijević
3,4-methylendioxymethamphetamine (MDMA, Ecstasy) is a psycho-stimulating agent. It is usually taken orally in the form of tablets. It is absorbed throught the gastrointestinal mucous membrane. Hyperthermia is the most prominent clinical sign of MDMA intake. The most prominent forensic finding of lethal MDMA poisoning is myocardial infarction and cerebrovascular bleeding. However, liver and...
Medicinski pregled
2009
Ivan Simic, Zivorad Malicevic
Introduction. The consumption of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is known to cause severe hyperthermia in humans. This is of extreme importance since ecstasy is often consumed at 'rave' parties, where dancing takes place in a warm environment, which may exacerbate the effect of MDMA on thermoregulation. The present study was performed in order to evaluate the effects of single...
Nephrology
February 2008
Milica Ninković, Vesna Selaković, Mirjana Dukić et al.
The mechanism of MDMA (3,4-methylenedioxymethamphetamine)-induced toxicity is believed to be, in part, due to enhanced oxidative stress. As MDMA is eliminated via the kidney, the aim of this study was to investigate whether MDMA created conditions of oxidative stress within rat kidney. Adult male Wistar rats were divided into three groups, control treatment (water), acute MDMA administration...
Medicinski pregled
2008
Ivan Simic, Zivorad Malicevic
Introduction Oxidative stress and oxygen free radicals are thought to play an important role in acute effects of a number of neurotoxic processes. 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy), a ring substituted amphetamine derivate, has attracted a great deal of media attention in recent years due to its widespread abuse as recreational drug by the young generation. The aim of the present...
Vojnosanitetski Pregled
2005
Zivorad Malicevic, Milica Ninković, Ivana Vasiljević et al.
Navedeni podaci ukazuju da ?ekstazi? nije, kako se to posebno medju omladinom smatra, laka, bezopasna i zabavna droga. Obilje nezeljenih psihickih, neuroloskih, hepatickih, bubreznih, kardiovaskularnih i drugih toksicnih efekata pokazuje samo da oni nisu dobro procenjeni, a najopasnije je sto se desavaju pri upotrebi uobicajenih prosecnih doza ove droge. Uzivaoci u vecini slucajeva prelaze...