Treatment of compulsive behaviour in eating disorders with intermittent ketamine infusions
QJM July 1, 1998 Ian G. Mills 92 citations
We have previously shown that eating disorders are a compulsive behaviour disease, characterized by frequent recall of anorexic thoughts. Evidence suggests that memory is a neocortical neuronal network, excitation of which involves the hippocampus, with recall occurring by re-excitement of the same specific network. Excitement of the hippocampus by glutamate-NMDA receptors, leading to long-term...