Adolescent substance use is associated with increased risk of suicide, overdose, and executive dysfunction. Alcohol and marijuana are the two most-used substances among young people. Substance use is associated with dysfunctional resting-state network connectivity between the default mode network (DMN), executive control network (ECN), and salience network (SN) and executive dysfunction. There...
Cannabis and tobacco use are highly prevalent among people with psychosis and are associated with medical comorbidities and poor prognosis. Concurrent use of cannabis and tobacco (‘co-use’) is rising in the general population, but has not been studied in psychosis. Given the devastating consequences of cannabis and tobacco use, it is critical to understand how their co-use affects psychiatric...