Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose-response relationship and clinical value of biomarkers remain unclear. This study aimed to characterize the demographics, patterns of use, outcomes, and biomarker utility in...
Clinical ToxicologyNovember 2021Darren M Roberts, Kulanka H Premachandra, Betty S. Chan et al.
Adulteration, substitution or contamination of illicit substances can have clinically significant implications when other illicit substances are included. Such circumstances can present as clusters of poisonings, including severe toxicity and death following exposure to unexpected illicit substances. We report a cluster of laboratory-confirmed lysergic acid diethylamide (LSD) in a powder that...
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi et al.
Aims: Recreational nitrous oxide (N 2 O) misuse is a growing problem. It can cause functional hydroxycobalamin (B 12 ) deficiency and severe neurological complications. Despite increasing harms, the dose-response relationship and clinical value of biomarkers remain unclear. This study aimed to characterise the demographics, patterns of use, outcomes, and biomarker utility in patients...