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Palanisamy Amirthalingam

2 papers in the library · publishing 2026

Papers

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Real-World Effectiveness and Safety of Esketamine Nasal Spray in Treatment-Resistant Depression: A Retrospective Observational Study

Healthcare August 26, 2026 Mostafa A. Sayed Ali, Palanisamy Amirthalingam, Hanan Alshareef et al.

Background/Objectives: This study evaluated the real-world effectiveness and safety of intranasal esketamine plus oral antidepressants compared with venlafaxine-based oral antidepressant therapy in adults with moderate-to-severe treatment-resistant depression (TRD). Methods: This retrospective cohort study used electronic medical records from a mental health hospital between January 2023 and...

Neurotoxicity Linked to Nitrous Oxide (Galaxy Gas) Recreation: An Overview of Clinical Evidence

CNS & Neurological Disorders - Drug Targets March 18, 2026 Rajkapoor Balasubramanian, Naina Mohamed Pakkir Maideen, Krishnaveni Kandasamy et al.

Abstract: Nitrous oxide (N2O), known as laughing gas, is a colorless, low-volume gas that has become commonly used in busy maternity wards, emergency rooms, and dental offices. It provides an introduction to the principles and practices of anesthesia, sedation, and analgesia. This review examines the recreational use and prolonged exposure to nitrous oxide (N2O), both of which are associated...