Tales of the unexpected: psychedelic trial design solutions
Robin Carhart-Harris, Will Alexander Lucas, Lorenzo Pasquini et al. preprint
This article spotlights problematic assumptions and practices in clinical psychedelic research that together hamper the field’s ability to demonstrate causal identification, contributing to confusion and misunderstanding: (1) the main problematic assumption is that pretreatment expectancy causes therapeutic response; while expectancy predicts response to most treatments, it is becoming...