Conceptual analysis of mechanisms and methods in psychedelic clinical trial design: a narrative review
Therapeutic Advances in Psychopharmacology July 1, 2026 Martin Krsak, David Sparrow, Bernard Rosner et al.
Clinical trials with psychedelics face several challenges that are not present to such a degree with other pharmacotherapeutics. Psychedelic therapies often include a significant therapeutic container, including preparatory and integrative psychotherapy, along with supportive intervention during dosing sessions. All these are likely to have an effect on the outcomes. Additionally, the influence...
DOI: 10.1177/20451253261470523 (opens in new tab)
Expectancy theory
Clinical trial
Modalities
Intervention counseling
+5