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Thomas Lumley

2 papers in the library · 328 citations · publishing 2021

Papers

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Blinding and expectancy confounds in psychedelic randomized controlled trials

Expert Review of Clinical Pharmacology May 26, 2021 Suresh Muthukumaraswamy, Anna Forsyth, Thomas Lumley 312 citations

Introduction: There is increasing interest in the potential for psychedelic drugs such as psilocybin, LSD and ketamine to treat several mental health disorders, with a growing number of randomized controlled trials (RCTs) being conducted to investigate the therapeutic effectiveness of psychedelics.Areas covered: We review previous literature on expectancy effects and blinding in the context of...

Blinding and Expectancy Confounds in Psychedelic Randomised Controlled Trials

March 8, 2021 Suresh Muthukumaraswamy, Anna Forsyth, Thomas Lumley 16 citations preprint

There is increasing interest in the potential for psychedelic drugs such as psilocybin, LSD and ketamine to treat a number of mental health disorders. To gain evidence for the therapeutic effectiveness of psychedelics, a number of randomised controlled trials (RCTs) have been conducted using the traditional RCT framework and these trials have generally shown promising results, with large effect...