Effects of nitrous oxide on psychological performance. A dose-response study using inhalation of concentrations up to 15%.
Psychopharmacology February 1, 1995 P J Armstrong, C Morton, W Sinclair et al.
In this six-period randomised double-blind study, 12 healthy volunteers inhaled mixtures of nitrous oxide at concentrations of 0% (placebo); 3%, 5%, 7%, 10%, and 15% in oxygen. Each concentration was inhaled for 55 min, each period being on a separate day. The order of treatments was randomised using a Latin-Square design. The effects of nitrous oxide were assessed using a battery of...