According to the 4-D model of Frewen and Lanius, trauma-related altered states of consciousness (TRASC) involve an alteration of the dimension of time and memory which divides the symptoms of post traumatic stress disorder (PTSD) into those which occur in “Normal Waking Consciousness” (NWC) and those which present dissociative experiences as part of TRASC. The present report addresses the...
Current antipsychotics have limited efficacy in controlling cognitive and negative symptoms of schizophrenia (SZ). Glutamatergic dysregulation has been implicated in the pathophysiology of SZ, based on the capacity of N-methyl-D-aspartate receptor (NMDAR) antagonists such as ketamine (KET) to induce SZ-like behaviors. This could be related to their putative neuropathological effect on...