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Kenneth J. Sufka

2 papers in the library · publishing 2014-2025

Papers

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Synbiotic diet produces antidepressant-like effects but alters ketamine activity in an avian model of treatment-resistant depression

Behavioural Pharmacology August 21, 2025 Stephen W. White, Tara D. Clover, Kenneth J. Sufka

Pre- and probiotics promote a diverse and functional gut microbiota and have demonstrated both anxiolytic and antidepressant effects; however, how synbiotic diet interacts with antidepressant medications has not been fully investigated. This study sought to evaluate the potential anxiolytic or antidepressant effects of a synbiotic diet in an avian model that presents homologies with...

The effect of Salvia divinorum and Mitragyna speciosa extracts, fraction and major constituents on place aversion and place preference in rats.

Journal of Ethnopharmacology 2014 Kenneth J. Sufka, Melissa J Loria, Kevin Lewellyn et al.

Consumer use of botanicals has increased despite, in many instances, the paucity of research demonstrating efficacy or identifying liabilities. This research employed the place preference/aversion paradigm to characterize the psychoactive properties of Salvia divinorum extract (10, 30, 100mg/kg), salvinorin A (0.1, 0.3, 1.0mg/kg), Mitragyna speciosa MeOH extract (50, 100, 300 mg/kg), Mitragyna...