An automated method for measurement of methoxetamine in human plasma by use of turbulent flow on-line extraction coupled with liquid chromatography and mass spectrometric detection.
Analytical and Bioanalytical Chemistry January 1, 2013 Emuri Abe, Florian Ricard, François Darrouzain et al.
A new laboratory method using automated sample preparation and liquid chromatography with mass spectrometry accurately measures methoxetamine, a ketamine-like designer drug, in human plasma. The assay is precise and reliable over a concentration range of 2.0 to 1000.0 ng/mL, with no matrix interference. The method was applied to a French case of acute intoxication, where the patient's plasma concentration was 136 ng/mL.