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Anna Mura

1 paper in the library · publishing 1993

Papers

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MK‐801, phencyclidine (PCP), and PCP‐like drugs increase burst firing in rat A10 dopamine neurons: Comparison to competitive NMDA antagonists

Synapse February 1, 1993 Edward D. French, Anna Mura, Ting Wang

AbstractExtracellular single‐unit recordings were used to assess the effects of PCP and PCP‐like drugs (MK‐801 and TCP) on the burst firing of ventral tegmental A10 dopamine neurons in the rat. The effects of these noncompetitive N‐methyl‐D‐aspartate (NMDA) receptor antagonists were compared to the potent and competitive NMDA antagonists CGS 19755 and (±)CPP, and to BTCP, a PCP‐derivative...