Spatiotemporal complexity in the psychotic brain.
Molecular Psychiatry April 1, 2026 Qiang Li, Jingyu Liu, Godfrey D Pearlson et al.
Psychotic disorders, such as schizophrenia and bipolar disorder, pose significant diagnostic challenges with major implications on mental health. The measures of resting-state fMRI spatiotemporal complexity offer a powerful tool for identifying irregularities in brain activity. To capture global brain connectivity, we employed information-theoretic metrics, overcoming the limitations of...