Science
September 3, 2026
Mario Heles, Lilach Pasvolsky, Hinduja Sathishkumar et al.
Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this work, we show that as little as two doses of psilocybin before chemotherapy durably prevented the onset of CIPN across platinum- and taxane-based models, including repeated chemotherapy cycles,...
Journal of Integrative and Complementary Medicine
October 1, 2024
Richard W Wagner, Smitha Mallaiah, Clark R Anderson et al.
Introduction: During the COVID-19 pandemic, health care workers (HCWs) experienced increased anxiety, depression, loneliness, and other mental health issues. HCWs need additional resources to cope with the mental health impact of their work. Yoga techniques could be helpful strategies to manage different stressors during times of uncertainty. Methods: This prospective, single-arm, trial...
The Journal of Alternative and Complementary Medicine
August 1, 2021
Santhosshi Narayanan, Jegy Tennison, Lorenzo Cohen et al.
Objectives: The authors explored the feasibility of virtual yoga-based breathwork and meditation among health care workers (HCW) during the COVID-19 pandemic. Methods: Consented employees of a large cancer center accessed a video of breathwork called "Simha Kriya" to be practiced for 4 weeks. Results: Of 217 participants who expressed interest within 2 weeks, 90 were recruited to the study in 1...
Journal of the American College of Radiology : JACR
May 2019
Chelsea G Ratcliff, Sarah Prinsloo, Alejandro Chaoul et al.
Stereotactic breast biopsy (SBB) is a common, anxiety-producing procedure. Nonpharmacologic methods to manage acute anxiety are needed. In this single-blind trial, women were recruited before SBB and randomized in a 2:2:1 ratio to a single session of guided mindfulness-based meditation (GM; n = 30), focused breathing (FB; n = 30), or standard care (SC; n = 16). Anxiety and pain were assessed at...
Journal of Pain and Symptom Management
February 5, 2018
Gabriel Lopez, Alejandro Chaoul, Catherine Powers-James et al.
Context: Complementary health approaches such as meditation may help improve cancer patient and caregiver symptoms, yet little research has examined the clinical application of these programs. Objectives: We explored the effects of a meditation group class, offered as part of an integrative medicine clinic at a comprehensive cancer center, on patient and caregiver self-reported symptoms....
CrossCurrents
June 1, 2010
M. Alejandro Chaoul, Lorenzo Cohen
5 citations
Rethinking Yoga and the Application of Yoga in Modern Medicine M. Alejandro Chaoul and Lorenzo Cohen Yoga is a Sanskrit word that means union, to yoke, or to join; the merging of the microcosm of our existence in our body with the macrocosm. In the West, yoga is often referred to as a mind‐body technique from Asia, usually categorized as meditation (for those seated practices) and yoga...
Acta oncologica
November 22, 2008
Kelly A. Biegler, M. Alejandro Chaoul, Lorenzo Cohen
110 citations
BACKGROUND AND OBJECTIVES: Cancer-related cognitive impairment has been acknowledged as a substantial limiting factor in quality of life among cancer patients and survivors. In addition to deficits on behavioral measures, abnormalities in neurologic structure and function have been reported. In this paper, we review findings from the literature on cognitive impairment and cancer, potential...